What are they
The term “orodispersible” refers to a class of drugs formulated so that they can be dissolved in the mouth, without having to swallow the tablet and without the need for water.
Once the tablet is dissolved, the active ingredient is released: partly it is swallowed and partly absorbed directly by the oral mucosa.
This type of formulation, as well as those in sublingual pharmaceutical form, concerns different drugs and generally increases the effectiveness of the treatment and the speed with which the therapeutic effect arises.
Benefits
The part absorbed directly via the mucous membrane of the mouth enters directly into circulation, excluding both the passage of the active ingredient in the stomach where it can be partially deactivated and the so-called first-pass metabolism at the level of the liver, in which the transformation and elimination of most drugs generally takes place.
In this way the active substance reaches the bloodstream more quickly and in higher concentrations.
All this means that the therapeutic effect at the systemic level is faster.
In addition, to take orodispersible drugs it is not necessary to drink water, greatly facilitating the intake and allowing greater freedom for the patient.
It will also benefit subjects, perhaps of a certain age who have difficulty swallowing.
In general, there are no particular constraints, as is the case for all drugs to be taken by mouth, such as the indication to take them on an empty or full stomach, without constraints or unnatural rhythms.
Joycelyn Elders is the author and creator of EmpowerEssence, a health and wellness blog. Elders is a respected public health advocate and pediatrician dedicated to promoting general health and well-being.
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